Big differences between LSD & psilocybin?

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Albert Hoffman: [Do] you see big differences between LSD and psilocybin?

Terence McKenna: Surely. It seems LSD is only reluctantly a visionary hallucinogen. In terms of activity in the visual cortex, psilocybin is a fantastically prolific generator of visual hallucinations. Visual hallucinations are, I think, much more accessible to most people on psilocybin. However, the truly distinguishing quality between them... that the tryptamines have a quality of animation. There seems to be a Logos-like Other - an alien presence - not easily referenced to the components of the psyche. And it is animate, strange, and imbued with an alienness and a personality that is not present in LSD.
( from a talk given at Esalen Institute, Big Sur, California, Fall, 1984)

-pg. 50-51, THE ARCHAIC REVIVAL: Speculations on Psychedelic Mushrooms, the Amazon, Virtual Reality, UFOs, Evolution, Shamanism, the Rebirth of the Goddess, and the End of History by Terence McKenna, 1991