UpJohn Fluid Extract Ergot

Ergot derivatives have been reported to produce the following principal effects: uterotonic action, increase or decrease of blood-pressure, induction of hypothermia and emesis, control of the secretion of the pituitary hormones. They are mainly noradrenaline, serotonin or dopamine receptors mediated responses. No other group of substances exhibit such a widespread spectrum of biological actions. Their interactions with many receptor sites and the variation of activity and affinity from alkaloid to alkaloid are the main pharmacological features of the features of the ergot compounds. - from Ergot Alkaloids published by Sandoz Pharmaceuticals Department, 1986

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