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A semi-synthetic dimethylheptyl derivative of THC had first been produced in the late-1940s at the University of Illinois by the famous biochemist, Roger Adams, who had managed to isolate a related chemical called cannabidiol. The dimethylheptyl derivative was then tested on inmates Lexington Addiction Research Centre who... ...were used as guinea pigs in the CIA's MK-Ultra project. According to Abrams, the derivaive is, "about 50 times as powerful as LSD and like LSD, is active in the nanogram range."

pp. 77, ACID The Secret History of LSD by David Black (1998)

MK-Ultra, CIA, Lexington Addiction Research Centre, nanogram